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A preferred region for recombinational patch repair in the 5' untranslated region of primer binding site-impaired murine leukemia virus vectors.

Transduction of primer binding site-impaired Akv murine leukemia virus-based retroviral vectors from the murine packaging cell lines psi-2 and omega E was studied. The efficiency of transduction of the neo marker of all mutated constructs was found to decrease by 5 to 6 orders of magnitude compared...

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Détails bibliographiques
Publié dans:J Virol
Auteurs principaux: Mikkelsen, J G, Lund, A H, Kristensen, K D, Duch, M, Sørensen, M S, Jørgensen, P, Pedersen, F S
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology (ASM) 1996
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC189964/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8627661/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.70.3.1439-1447.1996
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