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A preferred region for recombinational patch repair in the 5' untranslated region of primer binding site-impaired murine leukemia virus vectors.

Transduction of primer binding site-impaired Akv murine leukemia virus-based retroviral vectors from the murine packaging cell lines psi-2 and omega E was studied. The efficiency of transduction of the neo marker of all mutated constructs was found to decrease by 5 to 6 orders of magnitude compared...

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Bibliografiske detaljer
Main Authors: Mikkelsen, J G, Lund, A H, Kristensen, K D, Duch, M, Sørensen, M S, Jørgensen, P, Pedersen, F S
Format: Artigo
Sprog:Inglês
Udgivet: 1996
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC189964/
https://ncbi.nlm.nih.gov/pubmed/8627661
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