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The role of CDK in the initiation step of DNA replication in eukaryotes

Cyclin-dependent kinases (CDKs) regulate the progression of the cell cycle in eukaryotes. One of the major roles of CDK is to promote chromosomal DNA replication. However, how CDKs promote DNA replication has been a long-standing question, because all the essential CDK substrates in DNA replication...

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Detalhes bibliográficos
Main Authors: Tanaka, Seiji, Tak, Yon-Soo, Araki, Hiroyuki
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1899495/
https://ncbi.nlm.nih.gov/pubmed/17547773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1747-1028-2-16
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