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Autophagy mitigates metabolic stress and genome damage in mammary tumorigenesis

Autophagy is a catabolic process involving self-digestion of cellular organelles during starvation as a means of cell survival; however, if it proceeds to completion, autophagy can lead to cell death. Autophagy is also a haploinsufficient tumor suppressor mechanism for mammary tumorigenesis, as the...

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Detalhes bibliográficos
Main Authors: Karantza-Wadsworth, Vassiliki, Patel, Shyam, Kravchuk, Olga, Chen, Guanghua, Mathew, Robin, Jin, Shengkan, White, Eileen
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1899472/
https://ncbi.nlm.nih.gov/pubmed/17606641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1565707
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