Genetic Mapping in Mice Identifies DMBT1 as a Candidate Modifier of Mammary Tumors and Breast Cancer Risk

Low-penetrance breast cancer susceptibility alleles seem to play a significant role in breast cancer risk but are difficult to identify in human cohorts. A genetic screen of 176 N2 backcross progeny of two Trp53(+/−) strains, BALB/c and C57BL/6, which differ in their susceptibility to mammary tumors...

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Hlavní autoři: Blackburn, Anneke C., Hill, Linda Z., Roberts, Amy L., Wang, Jun, Aud, Dee, Jung, Jimmy, Nikolcheva, Tania, Allard, John, Peltz, Gary, Otis, Christopher N., Cao, Qing J., Ricketts, Reva St. J., Naber, Stephen P., Mollenhauer, Jan, Poustka, Annemarie, Malamud, Daniel, Jerry, D. Joseph
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Investigative Pathology 2007
Témata:
Regular Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1899446/
https://ncbi.nlm.nih.gov/pubmed/17525270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2007.060512
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