Genetic Mapping in Mice Identifies DMBT1 as a Candidate Modifier of Mammary Tumors and Breast Cancer Risk

Low-penetrance breast cancer susceptibility alleles seem to play a significant role in breast cancer risk but are difficult to identify in human cohorts. A genetic screen of 176 N2 backcross progeny of two Trp53(+/−) strains, BALB/c and C57BL/6, which differ in their susceptibility to mammary tumors...

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Main Authors: Blackburn, Anneke C., Hill, Linda Z., Roberts, Amy L., Wang, Jun, Aud, Dee, Jung, Jimmy, Nikolcheva, Tania, Allard, John, Peltz, Gary, Otis, Christopher N., Cao, Qing J., Ricketts, Reva St. J., Naber, Stephen P., Mollenhauer, Jan, Poustka, Annemarie, Malamud, Daniel, Jerry, D. Joseph
Format: Artigo
Jezik:Inglês
Izdano: American Society for Investigative Pathology 2007
Teme:
Regular Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1899446/
https://ncbi.nlm.nih.gov/pubmed/17525270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2007.060512
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