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Reassessment of the Late Steps of Coenzyme B(12) Synthesis in Salmonella enterica: Evidence that Dephosphorylation of Adenosylcobalamin-5′-Phosphate by the CobC Phosphatase Is the Last Step of the Pathway
We report that cobC strains of Salmonella enterica serovar Typhimurium are impaired in the ability to salvage cobyric acid (Cby), a de novo corrin ring biosynthetic intermediate, under aerobic growth conditions. In vivo and in vitro evidence support the conclusion that this new phenotype of cobC str...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Society for Microbiology
2007
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| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1899380/ https://ncbi.nlm.nih.gov/pubmed/17209023 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.01665-06 |
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