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Amplification of lac Cannot Account for Adaptive Mutation to Lac(+) in Escherichia coli

When the Lac(−) strain of Escherichia coli, FC40, is incubated with lactose as its sole carbon and energy source, Lac(+) revertants arise at a constant rate, a phenomenon known as adaptive mutation. Two alternative models for adaptive mutation have been proposed: (i) recombination-dependent mutation...

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Detalhes bibliográficos
Main Authors: Stumpf, Jeffrey D., Poteete, Anthony R., Foster, Patricia L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1899370/
https://ncbi.nlm.nih.gov/pubmed/17209030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.01706-06
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