Integrin αvβ5 Regulates Lung Vascular Permeability and Pulmonary Endothelial Barrier Function

Increased lung vascular permeability is an important contributor to respiratory failure in acute lung injury (ALI). We found that a function-blocking antibody against the integrin αvβ5 prevented development of lung vascular permeability in two different models of ALI: ischemia-reperfusion in rats (m...

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Hauptverfasser: Su, George, Hodnett, Maki, Wu, Nanyan, Atakilit, Amha, Kosinski, Cynthia, Godzich, Mika, Huang, Xiao Zhu, Kim, Jiyeun K., Frank, James A., Matthay, Michael A., Sheppard, Dean, Pittet, Jean-François
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Thoracic Society 2007
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Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1899321/
https://ncbi.nlm.nih.gov/pubmed/17079779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2006-0238OC
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