Absence of Integrin αvβ3 Enhances Vascular Leak in Mice by Inhibiting Endothelial Cortical Actin Formation

Rationale: Sepsis and acute lung injury (ALI) have devastatingly high mortality rates. Both are associated with increased vascular leak, a process regulated by complex molecular mechanisms. Objectives: We hypothesized that integrin αvβ3 could be an important determinant of vascular leak and endothel...

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Autors principals: Su, George, Atakilit, Amha, Li, John T., Wu, Nanyan, Bhattacharya, Mallar, Zhu, Jieling, Shieh, Jennifer E., Li, Elizabeth, Chen, Robert, Sun, Stephen, Su, Cynthia P., Sheppard, Dean
Format: Artigo
Idioma:Inglês
Publicat: American Thoracic Society 2012
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Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3262039/
https://ncbi.nlm.nih.gov/pubmed/21980034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.201108-1381OC
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