Thyroid Transcription Factor in Differentiating Type II Cells: Regulation, Isoforms, and Target Genes

Thyroid transcription factor-1 (TTF-1, product of the Nkx2.1 gene) is essential for branching morphogenesis of the lung and enhances expression of surfactant proteins by alveolar type II cells. We investigated expression of two TTF-1 mRNA transcripts, generated by alternative start sites and coding...

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Bibliographic Details
Main Authors: Kolla, Venkatadri, Gonzales, Linda W., Gonzales, John, Wang, Ping, Angampalli, Sreedevi, Feinstein, Sheldon I., Ballard, Philip L.
Format: Artigo
Language:Inglês
Published: American Thoracic Society 2007
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Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1899316/
https://ncbi.nlm.nih.gov/pubmed/16960125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2006-0207OC
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