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Comparative sequence analysis of leucine-rich repeats (LRRs) within vertebrate toll-like receptors

BACKGROUND: Toll-like receptors (TLRs) play a central role in innate immunity. TLRs are membrane glycoproteins and contain leucine rich repeat (LRR) motif in the ectodomain. TLRs recognize and respond to molecules such as lipopolysaccharide, peptidoglycan, flagellin, and RNA from bacteria or viruses...

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Main Authors: Matsushima, Norio, Tanaka, Takanori, Enkhbayar, Purevjav, Mikami, Tomoko, Taga, Masae, Yamada, Keiko, Kuroki, Yoshio
格式: Artigo
語言:Inglês
出版: BioMed Central 2007
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1899181/
https://ncbi.nlm.nih.gov/pubmed/17517123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-8-124
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