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Proteolytic Degradation of SCOP in the Hippocampus Contributes to Activation of MAP Kinase and Memory
Because activation of Erk1/2 MAP kinase (MAPK) is critical for hippocampus-dependent memory, there is considerable interest in mechanisms for regulation of MAPK during memory formation. Here we report that MAPK and CREB-mediated transcription are negatively regulated by SCOP (SCN Circadian Oscillato...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2007
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1899088/ https://ncbi.nlm.nih.gov/pubmed/17382888 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2006.12.047 |
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