Vaccinia virions lacking core protein VP8 are deficient in early transcription.
When synthesis of the 25-kDa vaccinia virus core protein VP8 is repressed, mature virus particles of normal appearance are produced to approximately 80% of wild-type levels but these particles are over 100-fold less infectious than wild-type particles (D. Wilcock and G. L. Smith, Virology 202:294-30...
Bewaard in:
| Gepubliceerd in: | J Virol |
|---|---|
| Hoofdauteurs: | , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
American Society for Microbiology (ASM)
1996
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC189897/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8551633/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.70.2.934-943.1996 |
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