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Vaccinia virions lacking core protein VP8 are deficient in early transcription.

When synthesis of the 25-kDa vaccinia virus core protein VP8 is repressed, mature virus particles of normal appearance are produced to approximately 80% of wild-type levels but these particles are over 100-fold less infectious than wild-type particles (D. Wilcock and G. L. Smith, Virology 202:294-30...

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Bibliografiske detaljer
Main Authors: Wilcock, D, Smith, G L
Format: Artigo
Sprog:Inglês
Udgivet: 1996
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC189897/
https://ncbi.nlm.nih.gov/pubmed/8551633
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