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The two biological activities of human immunodeficiency virus type 1 Vpu protein involve two separable structural domains.

The human immunodeficiency virus type 1 (HIV-1) Vpu protein is an integral membrane phosphoprotein that induces CD4 degradation in the endoplasmic reticulum and enhances virus release from the cell surface. CD4 degradation is specific, requires phosphorylation of Vpu, and involves the interaction be...

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Main Authors: Schubert, U, Bour, S, Ferrer-Montiel, A V, Montal, M, Maldarell, F, Strebel, K
格式: Artigo
語言:Inglês
出版: 1996
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC189883/
https://ncbi.nlm.nih.gov/pubmed/8551619
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