Use of recombinant protein to identify a motif-negative human cytotoxic T-cell epitope presented by HLA-A2 in the hepatitis C virus NS3 region.

To define cytotoxic T-cell (CTL) epitopes, the common approach involving the use of a series of overlapping synthetic peptides covering the whole protein sequence is impractical for large proteins. Motifs identify only a fraction of epitopes. To identify human CTL epitopes in the NS3 region of hepat...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Kurokohchi, K, Akatsuka, T, Pendleton, C D, Takamizawa, A, Nishioka, M, Battegay, M, Feinstone, S M, Berzofsky, J A
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1996
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC189809/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8523531/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.70.1.232-240.1996
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