Use of recombinant protein to identify a motif-negative human cytotoxic T-cell epitope presented by HLA-A2 in the hepatitis C virus NS3 region.

To define cytotoxic T-cell (CTL) epitopes, the common approach involving the use of a series of overlapping synthetic peptides covering the whole protein sequence is impractical for large proteins. Motifs identify only a fraction of epitopes. To identify human CTL epitopes in the NS3 region of hepat...

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Detalhes bibliográficos
Main Authors: Kurokohchi, K, Akatsuka, T, Pendleton, C D, Takamizawa, A, Nishioka, M, Battegay, M, Feinstone, S M, Berzofsky, J A
Formato: Artigo
Idioma:Inglês
Publicado em: 1996
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC189809/
https://ncbi.nlm.nih.gov/pubmed/8523531
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