The carboxyl terminus of the murine MyD116 gene substitutes for the corresponding domain of the gamma(1)34.5 gene of herpes simplex virus to preclude the premature shutoff of total protein synthesis in infected human cells.

Ítems similars

• The gamma 1(34.5) gene of herpes simplex virus 1 precludes neuroblastoma cells from triggering total shutoff of protein synthesis characteristic of programed cell death in neuronal cells.
  per: Chou, J, et al.
  Publicat: (1992)
• The Second-Site Mutation in the Herpes Simplex Virus Recombinants Lacking the γ(1)34.5 Genes Precludes Shutoff of Protein Synthesis by Blocking the Phosphorylation of eIF-2α
  per: Cassady, Kevin A., et al.
  Publicat: (1998)
• The herpes simplex virus virulence factor ICP34.5 and the cellular protein MyD116 complex with proliferating cell nuclear antigen through the 63-amino-acid domain conserved in ICP34.5, MyD116, and GADD34.
  per: Brown, S M, et al.
  Publicat: (1997)
• Sequence of MyD116 cDNA: a novel myeloid differentiation primary response gene induced by IL6.
  per: Lord, K A, et al.
  Publicat: (1990)
• A novel oncolytic herpes simplex virus armed with the carboxyl-terminus of murine MyD116 has enhanced anti-tumour efficacy against human breast cancer cells
  per: Cheng, Lin, et al.
  Publicat: (2018)