An aspartic acid at amino acid 108 is required to rescue infectious virus after transfection of a poliovirus cDNA containing a CGDD but not SGDD amino acid motif in 3Dpol.

Lignende værker

• Enzymatic activity of poliovirus RNA polymerase mutants with single amino acid changes in the conserved YGDD amino acid motif.
  af: Jablonski, S A, et al.
  Udgivet: (1991)
• Mutation of the aspartic acid residues of the GDD sequence motif of poliovirus RNA-dependent RNA polymerase results in enzymes with altered metal ion requirements for activity.
  af: Jablonski, S A, et al.
  Udgivet: (1995)
• Amino acid substitutions in the poliovirus maturation cleavage site affect assembly and result in accumulation of provirions.
  af: Ansardi, D C, et al.
  Udgivet: (1995)
• Identification of terminal adenylyl transferase activity of the poliovirus polymerase 3Dpol.
  af: Neufeld, K L, et al.
  Udgivet: (1994)
• Interaction of aspartate aminotransferase with amino acids
  af: Scotto, P., et al.
  Udgivet: (1965)