A single hamster PrP amino acid blocks conversion to protease-resistant PrP in scrapie-infected mouse neuroblastoma cells.

Neurodegeneration caused by the transmissible spongiform encephalopathies is associated with the conversion of a normal host protein, PrP-sen, into an abnormal aggregated protease-resistant form, PrP-res. In scrapie-infected mouse neuroblastoma cells, mouse PrP-sen is converted into PrP-res but reco...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Priola, S A, Chesebro, B
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1995
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC189717/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7494285/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.69.12.7754-7758.1995
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