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A rabbitpox virus serpin gene controls host range by inhibiting apoptosis in restrictive cells.

Poxviruses are unique among viruses in encoding members of the serine proteinase inhibitor (serpin) superfamily. Orthopoxviruses contain three serpins, designated SPI-1, SPI-2, and SPI-3. SPI-1 encodes a 40-kDa protein that is required for the replication of rabbitpox virus (RPV) in PK-15 or A549 ce...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Veröffentlicht in:J Virol
Hauptverfasser: Brooks, M A, Ali, A N, Turner, P C, Moyer, R W
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 1995
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC189710/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7494278/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.69.12.7688-7698.1995
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