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Function of a 5'-end genomic RNA mutation that evolves during persistent mouse hepatitis virus infection in vitro.

Persistently infected cultures of DBT cells were established with mouse hepatitis virus strain A59 (MHV-A59), and the evolution of the MHV leader RNA and 5' end of the genome was studied through 119 days postinfection. Sequence analysis of independent clones demonstrated an overall mutation frequenc...

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Vydáno v:J Virol
Hlavní autoři: Chen, W, Baric, R S
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 1995
Témata:
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC189691/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7494259/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.69.12.7529-7540.1995
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