A Tat-induced auto-up-regulatory loop for superactivation of the human immunodeficiency virus type 1 promoter.

The virus-encoded Tat protein strongly activates transcription of human immunodeficiency virus (HIV). A well-recognized mechanism involves interaction of Tat with the nascent RNA transcript of the viral tar gene; mutation of tar greatly decreases activation by Tat. However, Tat still provides a low...

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Main Authors: Biswas, D K, Salas, T R, Wang, F, Ahlers, C M, Dezube, B J, Pardee, A B
Format: Artigo
Jezik:Inglês
Izdano: 1995
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC189681/
https://ncbi.nlm.nih.gov/pubmed/7494249
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