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Catalytic mechanism of Zn(2+)-dependent polyol dehydrogenases: kinetic comparison of sheep liver sorbitol dehydrogenase with wild-type and Glu(154)→Cys forms of yeast xylitol dehydrogenase
Co-ordination of catalytic Zn(2+) in sorbitol/xylitol dehydrogenases of the medium-chain dehydrogenase/reductase superfamily involves direct or water-mediated interactions from a glutamic acid residue, which substitutes a homologous cysteine ligand in alcohol dehydrogenases of the yeast and liver ty...
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| Main Authors: | , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
Portland Press Ltd.
2007
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1896283/ https://ncbi.nlm.nih.gov/pubmed/17343568 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20061384 |
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