An Elevated Level of Cholesterol Impairs Self-Assembly of Pulmonary Surfactant into a Functional Film

In adult respiratory distress syndrome, the primary function of pulmonary surfactant to strongly reduce the surface tension of the air-alveolar interface is impaired, resulting in diminished lung compliance, a decreased lung volume, and severe hypoxemia. Dysfunction coincides with an increased level...

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Detalhes bibliográficos
Main Authors: Leonenko, Zoya, Gill, Simardeep, Baoukina, Svetlana, Monticelli, Luca, Doehner, Jana, Gunasekara, Lasantha, Felderer, Florian, Rodenstein, Mathias, Eng, Lukas M., Amrein, Matthias
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2007
Assuntos:
Spectroscopy, Imaging, Other Techniques
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1896251/
https://ncbi.nlm.nih.gov/pubmed/17483162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.107.106310
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