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Direct Simulation of Protein-Mediated Vesicle Fusion: Lung Surfactant Protein B

We simulated spontaneous fusion of small unilamellar vesicles mediated by lung surfactant protein B (SP-B) using the MARTINI force field. An SP-B monomer triggers fusion events by anchoring two vesicles and facilitating the formation of a lipid bridge between the proximal leaflets. Once a lipid brid...

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Detalhes bibliográficos
Main Authors: Baoukina, Svetlana, Tieleman, D. Peter
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3042587/
https://ncbi.nlm.nih.gov/pubmed/20923647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2010.07.049
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