Canine and Human Visual Cortex Intact and Responsive Despite Early Retinal Blindness from RPE65 Mutation

BACKGROUND: RPE65 is an essential molecule in the retinoid-visual cycle, and RPE65 gene mutations cause the congenital human blindness known as Leber congenital amaurosis (LCA). Somatic gene therapy delivered to the retina of blind dogs with an RPE65 mutation dramatically restores retinal physiology...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Aguirre, Geoffrey K, Komáromy, András M, Cideciyan, Artur V, Brainard, David H, Aleman, Tomas S, Roman, Alejandro J, Avants, Brian B, Gee, James C, Korczykowski, Marc, Hauswirth, William W, Acland, Gregory M, Aguirre, Gustavo D
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science 2007
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC1896221/
https://ncbi.nlm.nih.gov/pubmed/17594175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pmed.0040230
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