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Biology of umbilical cord blood progenitors in bone marrow niches

Within the bone marrow (BM), hematopoietic progenitor cells (HPCs) are localized in poorly oxygenated niches where they interact with the surrounding osteoblasts (OBs) through VLA4/VCAM-1 engagement, and are exposed to interleukin-6 (IL-6), stem cell factor (SCF), and chemokines such as CXCL12 (OB f...

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Autori principali: Dao, Mo A., Creer, Michael H., Nolta, Jan A., Verfaillie, Catherine M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Hematology 2007
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1896129/
https://ncbi.nlm.nih.gov/pubmed/17371947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2006-08-034447
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