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Biology of umbilical cord blood progenitors in bone marrow niches

Within the bone marrow (BM), hematopoietic progenitor cells (HPCs) are localized in poorly oxygenated niches where they interact with the surrounding osteoblasts (OBs) through VLA4/VCAM-1 engagement, and are exposed to interleukin-6 (IL-6), stem cell factor (SCF), and chemokines such as CXCL12 (OB f...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Dao, Mo A., Creer, Michael H., Nolta, Jan A., Verfaillie, Catherine M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society of Hematology 2007
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1896129/
https://ncbi.nlm.nih.gov/pubmed/17371947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2006-08-034447
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