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Opening of connexin 43 hemichannels is increased by lowering intracellular redox potential

Nonjunctional membrane in many cells contains connexin gap junction hemichannels (or connexons) that can open to allow permeation of small molecules. Opening of Cx43 hemichannels is infrequent in normal extracellular Ca(2+) and enhanced by low Ca(2+), positive membrane potentials, and dephosphorylat...

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Main Authors: Retamal, Mauricio A., Schalper, Kurt A., Shoji, Kenji F., Bennett, Michael V. L., Sáez, Juan C.
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2007
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1895948/
https://ncbi.nlm.nih.gov/pubmed/17494739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0702456104
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