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Hematopoietic stem cell exhaustion impacted by p18(INK4C) and p21(Cip1/Waf1) in opposite manners

Transplantation-associated stress can compromise the hematopoietic potential of hematopoietic stem cells (HSCs). As a consequence, HSCs may undergo “exhaustion” in serial transplant recipients, for which the cellular and molecular bases are not well understood. Hematopoietic exhaustion appears to be...

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Hlavní autoři: Yu, Hui, Yuan, Youzhong, Shen, Hongmei, Cheng, Tao
Médium: Artigo
Jazyk:Inglês
Vydáno: © 2006 by The American Society of Hematology 2006
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1895913/
https://ncbi.nlm.nih.gov/pubmed/16234365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2005-02-0685
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