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Hematopoietic stem cell exhaustion impacted by p18(INK4C) and p21(Cip1/Waf1) in opposite manners
Transplantation-associated stress can compromise the hematopoietic potential of hematopoietic stem cells (HSCs). As a consequence, HSCs may undergo “exhaustion” in serial transplant recipients, for which the cellular and molecular bases are not well understood. Hematopoietic exhaustion appears to be...
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Huvudupphovsmän: | , , , |
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Materialtyp: | Artigo |
Språk: | Inglês |
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© 2006 by The American Society of Hematology
2006
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Ämnen: | |
Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1895913/ https://ncbi.nlm.nih.gov/pubmed/16234365 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2005-02-0685 |
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