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G-CSF down-regulation of CXCR4 expression identified as a mechanism for mobilization of myeloid cells

CXCR4 receptor expression is required for the retention of granulocyte precursors and mature neutrophils within the bone marrow, and disruption of the SDF-1/CXCR4 axis in the bone marrow results in the mobilization of myeloid lineage cells to the peripheral circulation. We report that G-CSF down-reg...

詳細記述

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書誌詳細
主要な著者: Kim, Hyun Kyung, De La Luz Sierra, Maria, Williams, Cassin Kimmel, Gulino, A. Virginia, Tosato, Giovanna
フォーマット: Artigo
言語:Inglês
出版事項: The American Society of Hematology 2006
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC1895847/
https://ncbi.nlm.nih.gov/pubmed/16537807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2005-10-4162
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