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G-CSF down-regulation of CXCR4 expression identified as a mechanism for mobilization of myeloid cells
CXCR4 receptor expression is required for the retention of granulocyte precursors and mature neutrophils within the bone marrow, and disruption of the SDF-1/CXCR4 axis in the bone marrow results in the mobilization of myeloid lineage cells to the peripheral circulation. We report that G-CSF down-reg...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The American Society of Hematology
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1895847/ https://ncbi.nlm.nih.gov/pubmed/16537807 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2005-10-4162 |
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