Chemokine receptor targeting efficiently directs antigens to MHC class I pathways and elicits antigen-specific CD8(+) T-cell responses

Chemokines are key controllers of cell trafficking and are involved in numerous pathologic and inflammatory conditions. However, the fate of a chemokine ligand, once it is endocytosed with its receptor, remains obscure. Here, using chemokine–tumor antigen fusion constructs, we demonstrate for the fi...

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Bibliografiske detaljer
Main Authors:	Schiavo, Roberta, Baatar, Dolgor, Olkhanud, Purevdorj, Indig, Fred E., Restifo, Nicholas, Taub, Dennis, Biragyn, Arya
Format:	Artigo
Sprog:	Inglês
Udgivet:	The American Society of Hematology 2006
Fag:	Chemokines, Cytokines, and Interleukins
Online adgang:	https://ncbi.nlm.nih.gov/pmc/articles/PMC1895803/ https://ncbi.nlm.nih.gov/pubmed/16514063 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2005-08-3207
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Chemokine receptor targeting efficiently directs antigens to MHC class I pathways and elicits antigen-specific CD8(+) T-cell responses

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