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High frequency of alternative first exons in erythroid genes suggests a critical role in regulating gene function

The human genome uses alternative pre-mRNA splicing as an important mechanism to encode a complex proteome from a relatively small number of genes. An unknown number of these genes also possess multiple transcriptional promoters and alternative first exons that contribute another layer of complexity...

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Detalhes bibliográficos
Main Authors: Tan, Jeff S., Mohandas, Narla, Conboy, John G.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society of Hematology 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1895744/
https://ncbi.nlm.nih.gov/pubmed/16293607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2005-07-2957
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