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Targeted gene deletion demonstrates that the cell adhesion molecule ICAM-4 is critical for erythroblastic island formation

Erythroid progenitors differentiate in erythroblastic islands, bone marrow niches composed of erythroblasts surrounding a central macrophage. Evidence suggests that within islands adhesive interactions regulate erythropoiesis and apoptosis. We are exploring whether erythroid intercellular adhesion m...

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Detalhes bibliográficos
Main Authors: Lee, Gloria, Lo, Annie, Short, Sarah A., Mankelow, Tosti J., Spring, Frances, Parsons, Stephen F., Yazdanbakhsh, Karina, Mohandas, Narla, Anstee, David J., Chasis, Joel Anne
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society of Hematology 2006
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1895542/
https://ncbi.nlm.nih.gov/pubmed/16690966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2006-03-006759
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