Selection based on CD133 and high aldehyde dehydrogenase activity isolates long-term reconstituting human hematopoietic stem cells

The development of novel cell-based therapies requires understanding of distinct human hematopoietic stem and progenitor cell populations. We recently isolated reconstituting hematopoietic stem cells (HSCs) by lineage depletion and purification based on high aldehyde dehydrogenase activity (ALDH(hi)...

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Bibliographic Details
Main Authors: Hess, David A., Wirthlin, Louisa, Craft, Timothy P., Herrbrich, Phillip E., Hohm, Sarah A., Lahey, Ryan, Eades, William C., Creer, Michael H., Nolta, Jan A.
Format: Artigo
Language:Inglês
Published: © 2006 by The American Society of Hematology 2006
Subjects:
Stem Cells in Hematology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1895716/
https://ncbi.nlm.nih.gov/pubmed/16269619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2005-06-2284
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