Zebrafish to humans: evolution of the α3-chain of type IV collagen and emergence of the autoimmune epitopes associated with Goodpasture syndrome

Goodpasture syndrome is an autoimmune vascular disease associated with kidney and lung failure, with pathogenic circulating autoantibodies targeted to a set of discontinuous epitope sequences within the noncollagenous domain-1 (NC1) of the α3 chain of type IV collagen (α3(IV)NC1), the Goodpasture au...

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Bibliographic Details
Main Authors: MacDonald, Brian A., Sund, Malin, Grant, Marianne A., Pfaff, Kathleen L., Holthaus, Kathryn, Zon, Leonard I., Kalluri, Raghu
Format: Artigo
Language:Inglês
Published: © 2006 by The American Society of Hematology 2006
Subjects:
Hemostasis, Thrombosis, and Vascular Biology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1895704/
https://ncbi.nlm.nih.gov/pubmed/16254142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2005-05-1814
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