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Hematopoiesis and stem cell renewal in long-term bone marrow cultures containing catalase

Culturing mouse bone marrow in the presence of catalase dramatically alters hematopoiesis. Granulocyte output is initially increased 4- to 5-fold. This increase is transient and granulocyte production declines as immature (Sca-1(+)/LIN(-)) cells accumulate. One third of these immature cells have a p...

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Detalhes bibliográficos
Main Authors: Gupta, Rashmi, Karpatkin, Simon, Basch, Ross S.
Formato: Artigo
Idioma:Inglês
Publicado em: © 2006 by The American Society of Hematology 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1895700/
https://ncbi.nlm.nih.gov/pubmed/16278309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2005-03-1180
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