Cross-clade neutralization of primary isolates of human immunodeficiency virus type 1 by human monoclonal antibodies and tetrameric CD4-IgG.

We have tested three human monoclonal antibodies (MAbs) IgG1b12, 2G12, and 2F5) to the envelope glycoproteins of human immunodeficiency virus type 1 (HIV-1), and a tetrameric CD4-IgG molecule (CD4-IgG2), for the ability to neutralize primary HIV-1 isolates from the genetic clades A through F and fro...

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Autores principales: Trkola, A, Pomales, A B, Yuan, H, Korber, B, Maddon, P J, Allaway, G P, Katinger, H, Barbas, C F, Burton, D R, Ho, D D
Formato: Artigo
Lenguaje:Inglês
Publicado: 1995
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC189569/
https://ncbi.nlm.nih.gov/pubmed/7474069
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