The inositol phosphatase SHIP-2 down-regulates FcγR-mediated phagocytosis in murine macrophages independently of SHIP-1

FcγR-mediated phagocytosis of IgG-coated particles is a complex process involving the activation of multiple signaling enzymes and is regulated by the inositol phosphatases PTEN (phosphatase and tensin homolog deleted on chromosome 10) and SHIP-1 (Src homology [SH2] domain-containing inositol phosph...

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Bibliographic Details
Main Authors: Ai, Jing, Maturu, Amita, Johnson, Wesley, Wang, Yijie, Marsh, Clay B., Tridandapani, Susheela
Format: Artigo
Language:Inglês
Published: The American Society of Hematology 2006
Subjects:
Phagocytes
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1895625/
https://ncbi.nlm.nih.gov/pubmed/16179375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2005-05-1841
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