Sox4 cooperates with Evi1 in AKXD-23 myeloid tumors via transactivation of proviral LTR

Myeloid leukemias in AKXD23 mice contain proviral insertions at Evi1, resulting in transcriptional activation. Although Evi1 is clearly involved in leukemia, gene transfer studies in mice with Evi1 fail to cause leukemia, arguing that cooperating events are necessary. We reanalyzed AKXD-23 tumors fo...

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Main Authors: Boyd, Kathryn E., Xiao, Ying-Yi, Fan, Kai, Poholek, Amanda, Copeland, Neal G., Jenkins, Nancy A., Perkins, Archibald S.
格式: Artigo
語言:Inglês
出版: The American Society of Hematology 2006
主題:
Neoplasia
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1895620/
https://ncbi.nlm.nih.gov/pubmed/16204320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2003-05-1626
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