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Elevated levels of homocysteine compromise blood-brain barrier integrity in mice

Elevated levels of plasma homocysteine (Hcy) correlate with increased risk of cardiovascular and Alzheimer diseases. We studied the effect of elevated Hcy on the blood-brain barrier (BBB) to explore the possibility of a vascular link between the 2 diseases. On a hyperhomocysteinemic diet, cystathion...

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Hlavní autoři: Kamath, Atul F., Chauhan, Anil K., Kisucka, Janka, Dole, Vandana S., Loscalzo, Joseph, Handy, Diane E., Wagner, Denisa D.
Médium: Artigo
Jazyk:Inglês
Vydáno: The American Society of Hematology 2006
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1895614/
https://ncbi.nlm.nih.gov/pubmed/16189268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2005-06-2506
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