Stable gene transfer and expression in human primary T cells by the Sleeping Beauty transposon system

The Sleeping Beauty (SB) transposon system is a nonviral DNA delivery system in which a transposase directs integration of an SB transposon into TA-dinucleotide sites in the genome. To determine whether the SB transposon system can mediate stable gene expression in human T cells, primary peripheral...

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Hlavní autoři: Huang, Xin, Wilber, Andrew C., Bao, Lei, Tuong, Dong, Tolar, Jakub, Orchard, Paul J., Levine, Bruce L., June, Carl H., McIvor, R. Scott, Blazar, Bruce R., Zhou, Xianzheng
Médium: Artigo
Jazyk:Inglês
Vydáno: The American Society of Hematology 2006
Témata:
Gene Therapy
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1895607/
https://ncbi.nlm.nih.gov/pubmed/16189271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2005-05-2133
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