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Src family kinases are important negative regulators of G-CSF-dependent granulopoiesis
Granulocyte colony-stimulating factor (G-CSF) is the principal cytokine regulating granulopoiesis. Truncation mutations of the G-CSF receptor (G-CSFR) are associated with the development of acute myeloid leukemia in patients with severe congenital neutropenia. Although increased proliferative signal...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , , , , , , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
© 2006 by The American Society of Hematology
2006
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1895577/ https://ncbi.nlm.nih.gov/pubmed/16772601 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2006-05-024307 |
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