Specific killing of multiple myeloma cells by (-)-epigallocatechin-3-gallate extracted from green tea: biologic activity and therapeutic implications

Epigallocatechin-3-gallate (EGCG), a polyphenol extracted from green tea, is an antioxidant with chemopreventive and chemotherapeutic actions. Based on its ability to modulate growth factor-mediated cell proliferation, we evaluated its efficacy in multiple myeloma (MM). EGCG induced both dose- and t...

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Autori principali: Shammas, Masood A., Neri, Paola, Koley, Hemanta, Batchu, Ramesh B., Bertheau, Robert C., Munshi, Vidit, Prabhala, Rao, Fulciniti, Mariateresa, Tai, Yu tzu, Treon, Steven P., Goyal, Raj K., Anderson, Kenneth C., Munshi, Nikhil C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: © 2006 by The American Society of Hematology 2006
Soggetti:
Neoplasia
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1895573/
https://ncbi.nlm.nih.gov/pubmed/16809610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2006-05-022814
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