Host MHC class II(+) antigen-presenting cells and CD4 cells are required for CD8-mediated graft-versus-leukemia responses following delayed donor leukocyte infusions

Following bone marrow transplantation, delayed donor leukocyte infusions (DLIs) can induce graft-versus-leukemia (GVL) effects without graft-versus-host disease (GVHD). These antitumor responses are maximized by the presence of host hematopoietic antigen-presenting cells (APCs) at the time of DLI. U...

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Detalhes bibliográficos
Main Authors: Chakraverty, Ronjon, Eom, Hyeon-Seok, Sachs, Jessica, Buchli, Jennifer, Cotter, Pete, Hsu, Richard, Zhao, Guiling, Sykes, Megan
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society of Hematology 2006
Assuntos:
Transplantation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1895539/
https://ncbi.nlm.nih.gov/pubmed/16757687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2006-03-007427
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