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STAT3 governs distinct pathways in emergency granulopoiesis and mature neutrophils

Granulocyte colony-stimulating factor (G-CSF) is essential for the host response to bacterial infection by controlling neutrophil production in the bone marrow. The G-CSF receptor (G-CSFR) activates the Jak/STAT pathway, although little is understood about how these signals regulate basal and stress...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Panopoulos, Athanasia D., Zhang, Ling, Snow, Jonathan W., Jones, Daniel M., Smith, Amber M., El Kasmi, Karim C., Liu, Fulu, Goldsmith, Mark A., Link, Daniel C., Murray, Peter J., Watowich, Stephanie S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The American Society of Hematology 2006
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1895456/
https://ncbi.nlm.nih.gov/pubmed/16888100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2006-02-003012
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